Product Description
The long-awaited story of the science, the business, the politics, the intrigue behind the scenes of the most ferocious competition in the history of modern science—the race to map the human genome.
On May 10, 1998, biologist Craig Venter, director of the Institute for Genomic Research, announced that he was forming a private company that within three years would unravel the complete genetic code of human life—seven years before the projected finish of the U.S. government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work.
At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society.
The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry.
From the Hardcover edition.
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 Scientific journalism at it's best
I picked up this book because I realized that I knew next to nothing about the human genome--one of the most significant scientific accomplishments of the century. Shreeve's explanation of what it is and why it matters while describing the dramatic intellectual, technical and commercial competition between the academic community and private venture capitalists--most notably Craig Ventor-- is spellbinding. The most painless way to familiarize yourself with recent human genome research. An outstandiing read.
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Hard to put down! ( keith4057 )
You don't need to be a scientist to be captivated by this book. This is a riveting story of the intersection of vision, ego, politics and the battle between commercial interests and publicly funded efforts to do nothing less than lay the foundation for the technology that will likely define this century.
This is not a dry chronicle of the scientific methods, technological and computational breakthroughs that made this great accomplishment possible. Rather, Shreeve manages to guide the layman through the intricacies of all of the above, while never loosing site of the more interesting story of the personalities and interactions among the key players in this story. There are lessons here for anyone - integrity, vision, politics, business, perception and the law of unintended consequences.
The best book I've read this year.
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A fascinating and exciting journey! ( iggy82 )
Firstly, I haven't even finished this book at the time of my writing this review, but I could no longer wait to comment on it.
The distinguished feature of this book is its style of writing. It is incredibly simple and straight forward, without any unncessary twist of language or logic. Although this is a depiction of the whole story behind the Human Genome Project, it reads like an epic tale of a breathtaking journey.
James Shreeve gives a close account of all the events that led up to sequencing of human genome, including politics, science, business, legal matters and personal relations. What's more, is that a lay reader who understands nothing about gene or molecular biology can learn a whole lot of things he didn't know before. While the book is not technical in biological and other scientific explanations, it is sufficient to explain to the lay reader about genes, their importance as well as their pharamaceutical value.
This book, like other reviewers have mentioned, is truly hard to put down. Highly recommended to everyone!!
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Stunning! Superlative! Exciting! ( jimeastonpe )
I could not put this book down. This is an engrossingly written glimpse into the people, politics and science of the Human Genome project(s). Extraordinarily well done. Uplifting.
Exciting. At times depressing. Full of real people at war with real problems and real results.
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Unveiling the meaning of life ( msrumsey )
This book is a must-read for anyone who wants to understand the future of science, medicine, and technology. Though I have been intrigued with the human genome project and the mapping of other life forms, I had never understood the process or knew the key players in the epic search to do so. James Shreeves' masterful account of this landmark achievement brings the complex and compelling venture into sharp focus. His narrative includes not only colorful and insightful quotes from those involved on all levels, but also offers cogent explanations of the technical and scientific issues in breakthrough biological data-processing that will eventually change all our lives.
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